tert-butyl N-{2-azaspiro[3.3]heptan-6-yl}carbaMate - Names and Identifiers
tert-butyl N-{2-azaspiro[3.3]heptan-6-yl}carbaMate - Physico-chemical Properties
Molecular Formula | C11H20N2O2
|
Molar Mass | 212.29 |
Density | 1.09 |
Boling Point | 329.0±42.0 °C(Predicted) |
pKa | 12.38±0.20(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Sensitive | Irritant |
MDL | MFCD11858159 |
tert-butyl N-{2-azaspiro[3.3]heptan-6-yl}carbaMate - Introduction
tert-Butyl 2-azaspiro[3.3]hept-6-ylcarbamate is an organic compound with the formula C11H20N2O2.
Nature:
-Appearance: Colorless liquid or crystalline solid
-Melting point: about 62°C
-Boiling point: about 329°C
-Solubility: Can be dissolved in organic solvents, such as ethanol and dichloromethane
-Chemical properties: The compound is a nucleophile, which easily reacts with other electrophiles. At the same time, it is also a basic compound.
Use:
-Drug synthesis: tert-Butyl 2-azaspiro[3.3]hept-6-ylcarbamate can be used to synthesize new drug molecules or intermediates. Its spirocyclic structure can enhance the biological activity of compounds, so it has potential application in drug research and development.
Preparation Method:
tert-Butyl 2-azaspiro[3.3] The preparation method of hept-6-ylcarbamate is relatively complicated and involves multi-step reactions. The usual synthetic procedure involves the reaction of heptanedione with other compounds, and the selective synthesis of the product can be achieved by adjusting the reaction conditions and the ratio of reactants.
Safety Information:
As it involves chemical synthesis and use, attention must be paid to the safe use of this compound. tert-Butyl 2-azaspiro[3.3]hept-6-ylcarbamate, as a nucleophile, is irritating, so safety measures should be taken when in contact with skin, eyes or respiratory tract, such as wearing protective gloves, goggles and suitable respirators. In addition, inhalation of the compound in aerosol form should be avoided to prevent possible toxic effects. During use and storage, it should also be away from open flames and heat sources, and ensure good ventilation to avoid vapor accumulation.
Last Update:2024-04-09 21:11:58